The Effect of alpha-tocopherol on Cholesterol and Lipoproteins Levels in Rats

A.A. Al-Juary, K.H.M. Al-Awwad and F.A. Al-Torahi

The effect of the alpha-tocopherol on the reduction of plasma cholesterol, HDL, and LDL have been investigated in rats. No significant differences were observed on the rate of body weight gain, food intake, and food efficiency of rats fed with diet supplemented with alpha-tocopherol. There were significant decreases in serum cholesterol, and LDL+VLDL of animals fed alpha-tocopherol supplementation compared to control. In contrast the HDL cholesterol showed no significant decrease in animal groups fed alpha-tocopherol compared to control group. The lowest bile acid levels were in feces of control group, and the highest levels were for the groups fed alpha-tocopherol supplementation.